This article provides an analysis of data on modern diagnostics, treatment methods and the value of rotoviruses in acute intestinal infections. According to modern data, rotavirus infection accounts for 20-60% of acute intestinal infections. Determination of rotaviruses in feces extract by enzyme immunoassay and polymerase chain reaction, are widely used today.

Currently, pelvic prolapse is a dangerous disease associated with the irreversible development of the pathology of the pelvic organs. The main cause of this pathological condition is the weakening or damage of the connective tissue-muscle structures of the pelvic floor.

The available surgical methods for the treatment of genital prolapse cannot guarantee the absence of complications in the postoperative period and relapse. In this article, we describe the possibilities of preventing postoperative complications and repeated episodes of prolapse of the genital organs of local hormonal therapy with conjugated estrogen (femistrone) preparations, which directly improves the regenerative processes in the tissues of the genitourinary system. Based on our clinical experience, we came to the conclusion about the high efficacy and safety of topical application of conjugated estrogen (femistrone) for 5-7 days in the preparation of the vaginal walls for surgical treatment.

This article analyzes the last 10-year review of the literature on the structure and factors of influence on the biofilm of microorganisms, collected materials on the results of the effects of substances of both plant origin and chemical nature. Information is given on whether they can contribute to the formation of biofilms or, on the contrary, to its destruction.

The aim of the study was to study the nature of developmental disorders in children and adolescents with masses of the Turkish saddle. Material and methods. 44 children and adolescents with large tumors of the Turkish saddle (TS) were under our supervision in the neuroendocrinology department of the RSNPMCE MH RUz. Of 44 sick girls there were 20, boys 24. The average age of girls was 12.1 years, boys - 12.8 years. By the nature of the pathology, the patients were divided into 5 groups: I group. - inactive pituitary adenomas (NAG) - 23 patients (52.3%); II gr. - Itsenko-Cushing's disease - 5 (11.4%); III gr. - craniopharyngioma - 6 (13.6%); IV gr. - prolactinoma - 5 b-x (11.4%); V gr. - germinoma - 5 bx (11.4%). Results. The results obtained indicate that in children and adolescents there are TJ masses of various origins: inactive pituitary adenomas (52%), craniopharyngiomas (13.6%), corticotropinomas (11.4%), prolactinomas (11.4%), and others. The presence of diabetes insipidus (8.6%) indicates the severity of panhypopituitarism that developed as a result of the tumor. Conclusions: 1) disorders of growth and puberty are the most frequent manifestations of pituitary gland masses (34.0%), 2) pituitary tumors in children and adolescents often lead to hypo- and panhypopituitarism (n = 19, or 43.2%).

Fetal hypoxia is the leading cause of neonatal mortality and morbidity. The modern view on the problems of fetal hypoxia is that an insignificant effect of oxygen deficiency in the early phase of intrauterine development has been established, while hypoxia during organogenesis in the 2nd and 3rd trimesters of pregnancy can cause fatal consequences.