Analysis of the association of the polymorphic locus rs3218536 of the xrcc2 gene with the risk of developing ovarian cancer in women from the Republic of Bashkortosta
https://doi.org/10.21626/innova/2024.1/07
Abstract
Ovarian cancer is the most aggressive form of all malignant neoplasms of the female reproductive system. Despite certain advances achieved in the diagnosis and treatment of this disease, survival rates are still unsatisfactory, which dictates the need for further study of the etiological factors and pathogenetic mechanisms underlying ovarian carcinogenesis. The purpose of the work was to conduct an association analysis of the rs3218536 polymorphic variant of the XRCC2 gene with the risk of developing ovarian cancer in women from the Republic of Bashkortostan. As a result of the study, it was not possible to detect an association of the studied polymorphic locus with the risk of developing ovarian cancer in women from the Republic of Bashkortostan
Supporting agencies: Работа выполнена при финансовой поддержке Министерства науки и высшего образования РФ (№075-03-2021-193/5) и гранта Президента РФ (соглашение № 75-15-2023-329 от 22.02.23 г.).
About the Authors
Elvira Tagirovna Mingazheva
Ufa University of Science and Technology
Russian Federation
Russian Federation
Candidate of Biological Sciences
Yana Valerievna Valova
Ufa University of Science and Technology; Ufa scientific research institute of occupational medicine and human ecology
Russian Federation
Russian Federation
Daria Simonovna Prokofieva
Ufa University of Science and Technology
Russian Federation
Russian Federation
Candidate of Biological Sciences
Ekaterina Anatolevna Andreeva
Ufa University of Science and Technology
Russian Federation
Russian Federation
Rania Razyapovna Faishkhanova
Republican Clinical Oncology Dispensary of the Ministry of Health of the Republic of Bashkortostan
Russian Federation
Russian Federation
Candidate of Medical Sciences
Elza Kamilevna Khusnutdinova
Ufa University of Science and Technology;The institute of biochemistry and genetics of the Ufa federal research center of the R ussian academy of sciences
Russian Federation
Russian Federation
Doctor of Biological Sciences
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Review
For citations:
Mingazheva E.T., Valova Ya.V., Prokofieva D.S., Andreeva E.A., Faishkhanova R.R., Khusnutdinova E.K. Analysis of the association of the polymorphic locus rs3218536 of the xrcc2 gene with the risk of developing ovarian cancer in women from the Republic of Bashkortosta. Innova. 2024;10(1):36-39. (In Russ.) https://doi.org/10.21626/innova/2024.1/07
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